Chapter 5. Results

Table of Contents
5.1. Cadaveric and patient cancellous core dimensions and perforations of the medial iliac cortical plate
5.2. Clinical course of anterior iliac crest harvesting methods
5.3. Cranio-maxillofacial reconstruction with coral-derived granules
5.4. Dento-alveolar reconstruction with coral-derived granules

5.1. Cadaveric and patient cancellous core dimensions and perforations of the medial iliac cortical plate

The first three studies produced a total of 849 cancellous cores that were harvested as shown in Table 6.

Table 6. Total number of cancellous cores harvested in studies I, II and III.

StudyNumber of cancellous cores harvested
I250 from cadavers
40 from living patients
II333
III226
Total Cores849

In study I the bone harvested by the trephine took the form of a discrete and compact core of corticocancellous bone (Figs 5 & 13). The average core length was shorter than the core cutter, evidence of the core being compacted. In the cadaver (n = 250 cores), the average core length was 33.5 mm (range 28 to 38 mm, S.D. = 13.9). Each core had a diameter of 4 mm. The shortest cores were also the least compact and came from the most atrophic cadavers. The average weight of each core was 0.44 grams (range 0.37 to 0.49 grams, SD = 0.001). Each core occupied an average volume of 0.42 ml (range 0.35 to 0.48, SD = 0.002).

Perforations of the cortex of the iliac crest occurred in 11 out of 250 core samples (4.4% of cores). Four perforations occurred on the medial aspect and 7 occurred on the lateral aspect. Six perforations occurred on the closed side and 5 on the open side, which had the periosteum reflected. All perforations occurred with cores greater than 30mm in depth. The perforations consisted of a fraying or removal of cortical bone without periosteal disruption in 4 of the 6 closed sites.

All 20 of the intentional perforations involved the periosteum of the medial aspect of the ilium and the iliacus muscle. None involved the peritoneum or peritoneal contents as the instrument used in conjunction with its funnel-shaped retractor was not long enough to permit this.

The samples obtained from the patients (n = 40 cores) had an average length of 34.1 mm (range 28 to 38 mm, SD = 12.4) and an average weight of 0.46 g (range 0.4 to 0.5 g, SD = 0.001) and an average volume of 0.46 ml (range 0.39 to 0.5, SD = 0.002). The patient group was not statistically different from the cadaveric group.

Figure 13. Histological section of a cancellous core with haematoxylin and eosin stain at 20x magnification. Note the largely cancellous structure of the core with minimal cortical bone on the superior-most aspect on the left side. The cancellous core is laden with endosteal cells.