| Δ3-Δ2-Enoyl-CoA isomerase from the yeast Saccharomyces cerevisiae: Molecular and structural characterization | ||
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The structure of the yeast Δ3-Δ2-enoyl-CoA isomerase was compared by superposition studies with the other known structures within the hydratase/isomerase superfamily. For these comparisons, the following PDB entries were used: 2-enoyl-CoA hydratase-1 (liganded with acetoacetyl-CoA, 1DUB; liganded with octanoyl-CoA, 2DUB), 4-CBA–CoA dehalogenase (1NZY), methylmalonyl-CoA decarboxylase (unliganded, 1EF8; liganded, 1EF9) and Δ3,5-Δ2,4-dienoyl-CoA isomerase (1DCI). All superpositions were done with the lsq option in O (Jones et al. 1991), using the Cα-atoms of 25 residues from β -strands as well as their equivalents in the other structures.