This thesis is based on the following articles, which are referred to in the text by Roman numerals:
I Hukkanen J, Hakkola J, Anttila S, Piipari R, Karjalainen A, Pelkonen O & Raunio H (1997) Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human broncho-alveolar macrophages and peripheral blood lymphocytes. Mol Carcinogenesis, 20: 224-230.
II Anttila S, Hukkanen J, Hakkola J, Stjernvall T, Beaune P, Edwards RJ, Boobis AR, Pelkonen O & Raunio H (1997) Expression and localization of CYP3A4 and CYP3A5 in human lung. Am J Respir Cell Mol Biol 16: 242-249.
III Hukkanen J, Lassila A, Päivärinta K, Valanne S, Sarpo S, Hakkola J, Pelkonen O & Raunio H (2000) Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line. Am J Respir Cell Mol Biol 22: 360-366.
IV Hukkanen J, Hakkola J, Lassila A, Piipari R, Anttila S, Pelkonen O & Raunio H (2001) Modulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells. Manuscript.