|Surgical organ perfusion method for somatic gene transfer: An experimental study on gene transfer into the kidney, spleen, lung and mammary gland|
Transplanted organ from a different individual inside species (e.g. from donor human to recipient human).
A short segment of DNA, which binds to complementary messengerRNA so that the encoded protein is not produced.
A gene manifests itself by the gene product it encodes. The product is observed in a cell or secreted from a cell.
A short, defined sequence of nucleotides joined together in the typical phosphodiester linkage.
The site on the DNA molecule at which an enzyme called RNA polymerase binds to initiate gene transcription with the formation of messenger RNA.
The altered DNA that results from the insertion of a sequence of deoxynucleotides not previously present into an existing molecule of DNA by enzymatic or chemical means.
Multiplication, a process which duplicates e.g. DNA before cell division.
Catalytic RNA, which cleaves certain target RNA and thus prohibits the gene function.
Insertion of the desired exogenous gene into the proper cell (usually by retrovirusvector).
Insertion of the desired exogenous gene into the proper cell by viral or physical methods.
A foreign new gene introduced into a cell.
A vehicle plasmid or bacteriophage into which foreign DNA can be introduced for the purposes of gene transfer.
Transplanted organ from different species (e.g. from pig to human).